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| 1st(1st leg) | Zamalek | - | Wydad AC | 4:0 | ||
| 2nd (2nd leg) | Wydad AC | - | Zamalek | 5:2 | ||
| 1st(1st leg): 16/09/2016 19:00 | 2nd (2nd leg): 24/09/2016 21:00 | Winner: Zamalek | ||||
| 1st(1st leg) | ZESCO United | - | Mamelodi Sundowns | 2:1 | ||
| 2nd (2nd leg) | Mamelodi Sundowns | - | ZESCO United | 2:0 | ||
| 1st(1st leg): 17/09/2016 14:30 | 2nd (2nd leg): 24/09/2016 18:00 | Winner: Mamelodi Sundowns | ||||
