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| 1st(1st leg) | La Equidad | - | Millonarios | 1:1 (0:1) | ||
| 2nd (2nd leg) | Millonarios | - | La Equidad | 2:1 (1:0) | ||
| 1st(1st leg): 26/11/2017 00:30 | 2nd (2nd leg): 30/11/2017 00:45 | Winner: Millonarios | ||||
| 1st(1st leg) | Jaguares de Córdoba | - | Santa Fe | 0:0 (0:0) | ||
| 2nd (2nd leg) | Santa Fe | - | Jaguares de Córdoba | 4:1 (1:0) | ||
| 1st(1st leg): 26/11/2017 20:10 | 2nd (2nd leg): 30/11/2017 23:45 | Winner: Santa Fe | ||||
| 1st(1st leg) | Deportes Tolima | - | Atlético Nacional | 1:0 (0:0) | ||
| 2nd (2nd leg) | Atlético Nacional | - | Deportes Tolima | 1:3 (0:0, 2:1) pso | ||
| 1st(1st leg): 26/11/2017 22:05 | 2nd (2nd leg): 03/12/2017 00:45 | Winner: Deportes Tolima | ||||
| 1st(1st leg) | América de Cali | - | Atlético Junior | 0:0 (0:0) | ||
| 2nd (2nd leg) | Atlético Junior | - | América de Cali | 2:4 (2:1, 2:2) pso | ||
| 1st(1st leg): 28/11/2017 00:45 | 2nd (2nd leg): 03/12/2017 22:15 | Winner: América de Cali | ||||
