 |
| 1st(1st leg) | San Francisco FC | - | Seattle Sounders | 1:0 | ||
| 2nd (2nd leg) | Seattle Sounders | - | San Francisco FC | 2:0 aet | ||
| 1st(1st leg): 27/07/2011 01:00 | 2nd (2nd leg): 04/08/2011 03:00 | Winner: Seattle Sounders | ||||
| 1st(1st leg) | CS Herediano | - | Alpha United | 8:0 | ||
| 2nd (2nd leg) | Alpha United | - | CS Herediano | 2:2 | ||
| 1st(1st leg): 27/07/2011 03:00 | 2nd (2nd leg): 05/08/2011 01:00 | Winner: CS Herediano | ||||
| 1st(1st leg) | Toronto FC | - | Real Estelí FC | 2:1 | ||
| 2nd (2nd leg) | Real Estelí FC | - | Toronto FC | 1:2 | ||
| 1st(1st leg): 28/07/2011 01:00 | 2nd (2nd leg): 03/08/2011 03:00 | Winner: Toronto FC | ||||
| 1st(1st leg) | Isidro Metapán | - | Puerto Rico Islanders | 2:0 | ||
| 2nd (2nd leg) | Puerto Rico Islanders | - | Isidro Metapán | 3:1 | ||
| 1st(1st leg): 28/07/2011 01:00 | 2nd (2nd leg): 04/08/2011 01:00 | Winner: Isidro Metapán | ||||
| 1st(1st leg) | Santos Laguna | - | Olimpia | 3:1 | ||
| 2nd (2nd leg) | Olimpia | - | Santos Laguna | 2:1 (0:0) | ||
| 1st(1st leg): 28/07/2011 03:00 | 2nd (2nd leg): 04/08/2011 03:00 | Winner: Santos Laguna | ||||
| 1st(1st leg) | Monarcas Morelia | - | Tempête FC | 5:0 | ||
| 2nd (2nd leg) | Tempête FC | - | Monarcas Morelia | 0:2 | ||
| 1st(1st leg): 29/07/2011 01:00 | 2nd (2nd leg): 04/08/2011 01:00 | Winner: Monarcas Morelia | ||||
| 1st(1st leg) | Alianza | - | FC Dallas | 0:1 | ||
| 2nd (2nd leg) | FC Dallas | - | Alianza | 1:0 | ||
| 1st(1st leg): 29/07/2011 03:00 | 2nd (2nd leg): 04/08/2011 01:00 | Winner: FC Dallas | ||||
| 1st(1st leg) | Motagua | - | CSD Municipal | 4:0 | ||
| 2nd (2nd leg) | CSD Municipal | - | Motagua | 2:0 | ||
| 1st(1st leg): 29/07/2011 03:00 | 2nd (2nd leg): 05/08/2011 03:00 | Winner: Motagua | ||||
