1st(1st leg) Atlético Tucumán - Independiente 1:0 (1:0)
2nd (2nd leg) Independiente - Atlético Tucumán 2:0 (1:0)
1st(1st leg): 23/08/2017 01:45 2nd (2nd leg): 13/09/2017 01:45 Winner: Independiente
1st(1st leg) Club Nacional - Estudiantes 1:0 (0:0)
2nd (2nd leg) Estudiantes - Club Nacional 0:1 (0:0)
1st(1st leg): 24/08/2017 01:45 2nd (2nd leg): 19/09/2017 23:15 Winner: Club Nacional
1st(1st leg) Libertad - Santa Fe 1:0 (0:0)
2nd (2nd leg) Santa Fe - Libertad 1:1 (0:1)
1st(1st leg): 25/08/2017 01:45 2nd (2nd leg): 15/09/2017 01:45 Winner: Libertad
1st(1st leg) Cerro Porteño - Atlético Junior 0:0 (0:0)
2nd (2nd leg) Atlético Junior - Cerro Porteño 3:1 (1:0)
1st(1st leg): 13/09/2017 01:45 2nd (2nd leg): 20/09/2017 01:45 Winner: Atlético Junior
1st(1st leg) Chapecoense - Flamengo RJ 0:0 (0:0)
2nd (2nd leg) Flamengo RJ - Chapecoense 4:0 (2:0)
1st(1st leg): 13/09/2017 23:15 2nd (2nd leg): 20/09/2017 23:15 Winner: Flamengo RJ
1st(1st leg) Sport Recife - PE - Ponte Preta 3:1 (2:0)
2nd (2nd leg) Ponte Preta - Sport Recife - PE 1:0 (1:0)
1st(1st leg): 13/09/2017 23:15 2nd (2nd leg): 20/09/2017 23:15 Winner: Sport Recife - PE
1st(1st leg) Corinthians SP - Racing Club 1:1 (1:0)
2nd (2nd leg) Racing Club - Corinthians SP 0:0 (0:0)
1st(1st leg): 14/09/2017 01:45 2nd (2nd leg): 21/09/2017 01:45 Winner: Racing Club
1st(1st leg) Fluminense RJ - LDU Quito 1:0 (1:0)
2nd (2nd leg) LDU Quito - Fluminense RJ 2:1 (0:0)
1st(1st leg): 14/09/2017 23:15 2nd (2nd leg): 21/09/2017 23:15 Winner: Fluminense RJ