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| 1st(1st leg) | Atlético Madrid | - | Sevilla FC | 1:2 (0:0) | ||
| 2nd (2nd leg) | Sevilla FC | - | Atlético Madrid | 3:1 (1:1) | ||
| 1st(1st leg): 17/01/2018 18:00 | 2nd (2nd leg): 23/01/2018 20:30 | Winner: Sevilla FC | ||||
| 1st(1st leg) | Valencia CF | - | CD Alavés | 2:1 (0:0) | ||
| 2nd (2nd leg) | CD Alavés | - | Valencia CF | 2:3 (0:0, 2:1, 2:1) pso | ||
| 1st(1st leg): 17/01/2018 18:00 | 2nd (2nd leg): 24/01/2018 18:00 | Winner: Valencia CF | ||||
| 1st(1st leg) | Espanyol Barcelona | - | FC Barcelona | 1:0 (0:0) | ||
| 2nd (2nd leg) | FC Barcelona | - | Espanyol Barcelona | 2:0 (2:0) | ||
| 1st(1st leg): 17/01/2018 20:00 | 2nd (2nd leg): 25/01/2018 20:30 | Winner: FC Barcelona | ||||
| 1st(1st leg) | CD Leganés | - | Real Madrid | 0:1 (0:0) | ||
| 2nd (2nd leg) | Real Madrid | - | CD Leganés | 1:2 (0:1) | ||
| 1st(1st leg): 18/01/2018 20:30 | 2nd (2nd leg): 24/01/2018 20:30 | Winner: CD Leganés | ||||
