1st(1st leg) RSC Anderlecht - Manchester United 1:1 (0:1)
2nd (2nd leg) Manchester United - RSC Anderlecht 2:1 (1:1, 1:1) aet
1st(1st leg): 13/04/2017 20:05 2nd (2nd leg): 20/04/2017 20:05 Winner: Manchester United
1st(1st leg) Celta Vigo - KRC Genk 3:2 (3:1)
2nd (2nd leg) KRC Genk - Celta Vigo 1:1 (0:0)
1st(1st leg): 13/04/2017 20:05 2nd (2nd leg): 20/04/2017 20:05 Winner: Celta Vigo
1st(1st leg) AFC Ajax - FC Schalke 04 2:0 (1:0)
2nd (2nd leg) FC Schalke 04 - AFC Ajax 3:2 (0:0, 2:0) aet
1st(1st leg): 13/04/2017 20:05 2nd (2nd leg): 20/04/2017 20:05 Winner: AFC Ajax
1st(1st leg) Olympique Lyon - Beşiktaş 2:1 (0:1)
2nd (2nd leg) Beşiktaş - Olympique Lyon 6:7 (1:1, 2:1, 2:1) pso
1st(1st leg): 13/04/2017 20:50 2nd (2nd leg): 20/04/2017 20:05 Winner: Olympique Lyon