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| 16/03/2018 | 16:00 | Club León II | - | Pacific F. C. | 1:2 | |
| 16:00 | Lobos BUAP II | - | CF América II | 1:0 | ||
| 17:00 | CD Veracruz II | - | Pioneros de Cancún | 1:1 | ||
| 18:00 | Gallos Blancos II | - | Puebla FC II | 1:1 | ||
| 18:00 | CF Pachuca II | - | Reboceros de La Piedad | 0:2 | ||
| 21:00 | Cruz Azul Hidalgo | - | Real Zamora | 3:0 | ||
| 17/03/2018 | 01:00 | Tecos Fútbol Club | - | Dorados UACH | 2:0 | |
| 02:00 | Alacranes de Durango | - | Deportivo Guadalajara II | 2:0 | ||
| 16:00 | Deportivo Toluca II | - | Cruz Azul II | 0:2 | ||
| 18:00 | Monarcas Morelia II | - | Deportivo Tepic | 1:2 | ||
| 22:00 | Tuxtla FC | - | Halcones de Morelos | 2:1 | ||
| 22:00 | Loros UCOL | - | Atlas Guadalajara II | 4:2 | ||
| 22:00 | Tepatitlán | - | CF Monterrey II | 1:1 | ||
| 22:00 | Gavilanes de Matamoros | - | Santos Laguna II | 0:0 | ||
| 18/03/2018 | 01:00 | Inter Playa | - | Sporting Canamy | 3:0 | |
| 17:00 | Club Necaxa II | - | Club Tijuana II | 1:1 | ||
| 21:00 | Club Irapuato | - | Pumas UNAM II | 3:1 | ||
| 20/03/2018 | 00:00 | Atlético Reynosa | - | UANL Tigres II | 1:0 |
| » Tables | Home | Away | First round | Second round |
| 1 | |||||||||
| # | Team | M. | W | D | L | goals | Dif. | Pt. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Loros UCOL | 12 | 7 | 2 | 3 | 24:12 | 12 | 25 |
| 2 |
|
Club Necaxa II | 12 | 6 | 4 | 2 | 14:7 | 7 | 23 |
| 3 |
|
Atlético Reynosa | 12 | 6 | 2 | 4 | 19:9 | 10 | 20 |
| 4 |
|
Alacranes de Durango | 12 | 5 | 3 | 4 | 17:14 | 3 | 19 |
| 5 |
|
UANL Tigres II | 12 | 5 | 3 | 4 | 14:11 | 3 | 19 |
| 6 |
|
Tecos Fútbol Club | 12 | 5 | 4 | 3 | 13:10 | 3 | 19 |
| 7 |
|
Tepatitlán | 12 | 5 | 3 | 4 | 14:12 | 2 | 19 |
| 8 |
|
Monarcas Morelia II | 12 | 4 | 6 | 2 | 15:14 | 1 | 19 |
| 9 |
|
Atlas Guadalajara II | 12 | 4 | 5 | 3 | 16:16 | 0 | 18 |
| 10 |
|
Deportivo Tepic | 12 | 5 | 2 | 5 | 10:16 | -6 | 18 |
| 11 |
|
Club León II | 12 | 5 | 1 | 6 | 10:14 | -4 | 16 |
| 12 |
|
Deportivo Guadalajara II | 12 | 3 | 6 | 3 | 11:12 | -1 | 15 |
| 13 |
|
Club Tijuana II | 12 | 3 | 5 | 4 | 20:18 | 2 | 14 |
| 14 |
|
Pacific F. C. | 12 | 3 | 4 | 5 | 10:16 | -6 | 14 |
| 15 |
|
Santos Laguna II | 12 | 3 | 3 | 6 | 13:17 | -4 | 12 |
| 16 |
|
Gavilanes de Matamoros | 12 | 2 | 5 | 5 | 10:20 | -10 | 12 |
| 17 |
|
Dorados UACH | 12 | 3 | 2 | 7 | 13:19 | -6 | 11 |
| 18 |
|
CF Monterrey II | 12 | 1 | 6 | 5 | 11:17 | -6 | 9 |
| 2 | |||||||||
| # | Team | M. | W | D | L | goals | Dif. | Pt. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Tuxtla FC | 12 | 9 | 1 | 2 | 24:9 | 15 | 28 |
| 2 |
|
Club Irapuato | 12 | 7 | 3 | 2 | 26:16 | 10 | 24 |
| 3 |
|
Reboceros de La Piedad | 12 | 7 | 2 | 3 | 20:13 | 7 | 24 |
| 4 |
|
CF América II | 12 | 6 | 1 | 5 | 18:13 | 5 | 20 |
| 5 |
|
Inter Playa | 12 | 4 | 7 | 1 | 13:11 | 2 | 20 |
| 6 |
|
Pioneros de Cancún | 12 | 6 | 1 | 5 | 12:13 | -1 | 19 |
| 7 |
|
Real Zamora | 12 | 4 | 4 | 4 | 15:14 | 1 | 18 |
| 8 |
|
Cruz Azul Hidalgo | 12 | 4 | 4 | 4 | 18:15 | 3 | 17 |
| 9 |
|
Gallos Blancos II | 12 | 3 | 6 | 3 | 16:14 | 2 | 16 |
| 10 |
|
Lobos BUAP II | 12 | 3 | 6 | 3 | 14:18 | -4 | 16 |
| 11 |
|
Halcones de Morelos | 12 | 3 | 6 | 3 | 9:9 | 0 | 15 |
| 12 |
|
Puebla FC II | 12 | 3 | 5 | 4 | 12:15 | -3 | 15 |
| 13 |
|
Deportivo Toluca II | 12 | 3 | 4 | 5 | 13:17 | -4 | 14 |
| 14 |
|
CD Veracruz II | 12 | 3 | 4 | 5 | 10:12 | -2 | 13 |
| 15 |
|
Cruz Azul II | 12 | 3 | 3 | 6 | 16:21 | -5 | 13 |
| 16 |
|
Sporting Canamy | 12 | 3 | 3 | 6 | 12:20 | -8 | 12 |
| 17 |
|
Pumas UNAM II | 12 | 2 | 2 | 8 | 17:26 | -9 | 10 |
| 18 |
|
CF Pachuca II | 12 | 2 | 4 | 6 | 11:20 | -9 | 10 |
