| Squad | Appearances | ||
| sorting |
| Name |  |
 |
 |
 |
 |
 |
 |
 |
 |
| Hélton | 2683' | 30 | 30 | - | 1 | - | 3 | - | - |
| Jackson Martínez | 2684' | 30 | 30 | - | 1 | 26 | - | - | - |
| Lucho González | 2306' | 29 | 29 | - | 20 | 6 | 3 | - | - |
| Nicolás Otamendi | 2610' | 29 | 29 | - | - | - | 4 | - | - |
| Danilo | 2472' | 28 | 28 | - | 2 | 2 | 1 | 1 | - |
| João Moutinho | 2384' | 27 | 27 | - | 5 | 1 | 3 | - | - |
| Alex Sandro | 2149' | 25 | 24 | 1 | 1 | 1 | 6 | - | - |
| Steven Defour | 1299' | 25 | 14 | 11 | 11 | 2 | 1 | - | - |
| Varela | 1618' | 25 | 19 | 6 | 17 | 4 | 3 | - | - |
| Fernando | 1925' | 24 | 23 | 1 | 6 | 1 | 9 | - | - |
| James Rodríguez | 1748' | 24 | 19 | 5 | 9 | 10 | 4 | - | - |
| Eliaquim Mangala | 2017' | 23 | 22 | 1 | 1 | 4 | 6 | 1 | - |
| Christian Atsu | 682' | 17 | 9 | 8 | 8 | 1 | 1 | - | - |
| Andre Castro | 253' | 17 | - | 17 | - | 1 | - | - | - |
| Maicon | 985' | 15 | 12 | 3 | 3 | 2 | 1 | - | - |
| Marat Izmailov | 523' | 13 | 6 | 7 | 4 | 1 | 2 | - | - |
| Kelvin | 161' | 8 | 1 | 7 | 1 | 3 | - | - | - |
| Abdoulaye Ba | 330' | 6 | 2 | 4 | - | - | 1 | - | - |
| Liédson | 54' | 6 | - | 6 | - | - | - | - | - |
| Kléber | 91' | 5 | - | 5 | - | - | - | - | - |
| Sebá | 84' | 4 | - | 4 | - | - | - | - | - |
| Hulk | 270' | 3 | 3 | - | - | 2 | - | - | - |
| Miguel Lopes | 180' | 2 | 2 | - | - | 1 | - | - | - |
| Fabiano | 17' | 1 | - | 1 | - | - | - | - | - |
| Juan Iturbe | 27' | 1 | - | 1 | - | - | - | - | - |
| Héctor Quiñones | 90' | 1 | 1 | - | - | - | - | - | - |
| Rolando | 4' | 1 | - | 1 | - | - | - | - | - |
| Tózé | 24' | 1 | - | 1 | - | - | - | - | - |
| Dellatorre | - | - | - | - | - | - | - | - | - |
| Jorge Fucile | - | - | - | - | - | - | - | - | - |
| Kadú | - | - | - | - | - | - | - | - | - |
| Sérgio Oliveira | - | - | - | - | - | - | - | - | - |
Portugal