Real Madrid defender Pepe will miss Portugal's Euro 2016 qualifier at home to Serbia on Sunday because of slight concussion, national coach Fernando Santos revealed on Saturday.

"Pepe tried to recover from minor concussion this week but unfortunately will not play in Sunday's match," Santos told a pre-match press conference.

The Brazil-born defender was substituted after taking a knock playing for Real Madrid during last weekend's 2-1 loss to La Liga rivals Barcelona.

Portgual are currently second in Group I and one point behind Denmark, but with a game in hand, while Serbia are joint bottom of the pool with Armenia after picking up one point from three matches.