Brazil midfielder Luiz Gustavo faces a race against time to be fit for Wolfsburg's Champions League clash at Manchester United next Wednesday with a knee injury.

The defensive midfielder went off after 59 minutes of Tuesday's 5-1 defeat at Bayern Munich and is set to miss Saturday's league match at Hanover 96 as a precaution ahead of the Old Trafford encounter.

"For Luiz Gustavo, it could be tight, even for the match against Manchester," admitted Wolfsburg coach Dieter Hecking.

The 28-year-old has been suffering from a knee irritation for some time and jarred the joint in a clash with Bayern's Arturo Vidal.

Wolfsburg are second in Group B behind leaders PSV Eindhoven after their 1-0 win over CSKA Moscow, while United are third after their 2-1 defeat at the Dutch champions in the opening round of matches.