| 1. Round | 06/03/2022 | MŠK Žilina | - | Slovan Bratislava | 2:3 | ||||
| 2. Round | 12/03/2022 | Slovan Bratislava | - | MFK Ružomberok | 1:1 | ||||
| 3. Round | 19/03/2022 | Slovan Bratislava | - | ŠKF Sereď | 5:1 | ||||
| 4. Round | 03/04/2022 | Spartak Trnava | - | Slovan Bratislava | 0:1 | ||||
| 5. Round | 10/04/2022 | Slovan Bratislava | - | FC DAC 1904 | 3:1 | ||||
| 6. Round | 15/04/2022 | MFK Ružomberok | - | Slovan Bratislava | 0:0 | ||||
| 7. Round | 24/04/2022 | FC DAC 1904 | - | Slovan Bratislava | 2:0 | ||||
| 8. Round | 01/05/2022 | Slovan Bratislava | - | Spartak Trnava | 1:0 | ||||
| 10. Round | 21/05/2022 | Slovan Bratislava | - | MŠK Žilina | 2:2 |
Slovakia