| 4. Round | 14/08/2021 | Slovan Bratislava | - | MFK Zemplín Michalovce | 3:1 | ||||
| 5. Round | 22/08/2021 | ŠKF Sereď | - | Slovan Bratislava | 0:1 | ||||
| 6. Round | 29/08/2021 | Slovan Bratislava | - | Zlaté Moravce | 4:1 | ||||
| 7. Round | 12/09/2021 | FC DAC 1904 | - | Slovan Bratislava | 1:1 | ||||
| 11. Round | 17/10/2021 | Spartak Trnava | - | Slovan Bratislava | 0:3 dec. | ||||
| 13. Round | 31/10/2021 | AS Trenčín | - | Slovan Bratislava | 2:3 | ||||
| 15. Round | 21/11/2021 | MFK Zemplín Michalovce | - | Slovan Bratislava | 1:2 | ||||
| 17. Round | 03/12/2021 | Zlaté Moravce | - | Slovan Bratislava | 1:2 | ||||
| 18. Round | 12/12/2021 | Slovan Bratislava | - | FC DAC 1904 | 0:0 | ||||
| 20. Round | 12/02/2022 | Slovan Bratislava | - | FK Senica | 5:0 | ||||
| 22. Round | 26/02/2022 | Slovan Bratislava | - | Spartak Trnava | 0:0 |
Slovakia