| 1. Round | 17/01/2020 | Guaraní | - | San Lorenzo | 0:0 | ||||
| 8. Round | 08/03/2020 | San Lorenzo | - | Guaireña FC | 1:1 | ||||
| 9. Round | 22/07/2020 | General Díaz | - | San Lorenzo | 2:1 | ||||
| 10. Round | 25/07/2020 | San Lorenzo | - | Libertad | 1:2 | ||||
| 11. Round | 02/08/2020 | Cerro Porteño | - | San Lorenzo | 4:1 | ||||
| 12. Round | 09/08/2020 | San Lorenzo | - | Guaraní | 1:1 | ||||
| 13. Round | 13/08/2020 | 12 de Octubre de Itauguá | - | San Lorenzo | 1:0 | ||||
| 14. Round | 17/08/2020 | San Lorenzo | - | Club Olimpia | 2:2 | ||||
| 15. Round | 21/08/2020 | Club Nacional | - | San Lorenzo | 2:0 | ||||
| 16. Round | 26/08/2020 | San Lorenzo | - | River Plate | 0:0 | ||||
| 19. Round | 13/09/2020 | Guaireña FC | - | San Lorenzo | 4:0 |  |
Paraguay