| 1. Round | 23/07/2021 | FC Fredericia | - | Hobro IK | 2:0 | ||||
| 2. Round | 01/08/2021 | Nykøbing FC | - | FC Fredericia | 4:4 |  |
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| 3. Round | 09/08/2021 | Jammerbugt FC | - | FC Fredericia | 0:3 | ||||
| 4. Round | 13/08/2021 | FC Fredericia | - | Hvidovre IF | 1:0 | ||||
| 5. Round | 17/08/2021 | FC Fredericia | - | Esbjerg fB | 1:0 | ||||
| 6. Round | 22/08/2021 | Vendsyssel FF | - | FC Fredericia | 1:1 | ||||
| 7. Round | 27/08/2021 | FC Fredericia | - | Fremad Amager | 2:1 | ||||
| 8. Round | 12/09/2021 | AC Horsens | - | FC Fredericia | 1:3 | ||||
| 9. Round | 17/09/2021 | FC Fredericia | - | FC Helsingør | 2:4 | ||||
| 10. Round | 24/09/2021 | HB Køge | - | FC Fredericia | 3:0 | ||||
| 11. Round | 01/10/2021 | FC Fredericia | - | Lyngby BK | 0:2 | ||||
| 12. Round | 15/10/2021 | Fremad Amager | - | FC Fredericia | 0:1 | ||||
| 13. Round | 23/10/2021 | Esbjerg fB | - | FC Fredericia | 1:2 | ||||
| 15. Round | 08/11/2021 | FC Helsingør | - | FC Fredericia | 4:1 | ||||
| 16. Round | 21/11/2021 | FC Fredericia | - | Nykøbing FC | 3:2 | ||||
| 17. Round | 27/11/2021 | Hvidovre IF | - | FC Fredericia | 5:1 | ||||
| 18. Round | 03/12/2021 | FC Fredericia | - | AC Horsens | 0:2 |  |
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| 21. Round | 11/03/2022 | Hobro IK | - | FC Fredericia | 3:1 |
Denmark