1. Round 10/08/2019 Burnley FC - Southampton FC 3:0
10. Round 25/10/2019 Southampton FC - Leicester City 0:9
11. Round 02/11/2019 Manchester City - Southampton FC 2:1
12. Round 09/11/2019 Southampton FC - Everton FC 1:2
13. Round 23/11/2019 Arsenal FC - Southampton FC 2:2
14. Round 30/11/2019 Southampton FC - Watford FC 2:1
15. Round 04/12/2019 Southampton FC - Norwich City 2:1
16. Round 08/12/2019 Newcastle United - Southampton FC 2:1
17. Round 14/12/2019 Southampton FC - West Ham United 0:1
18. Round 21/12/2019 Aston Villa - Southampton FC 1:3 Goal
19. Round 26/12/2019 Chelsea FC - Southampton FC 0:2
20. Round 28/12/2019 Southampton FC - Crystal Palace 1:1
21. Round 01/01/2020 Southampton FC - Tottenham Hotspur 1:0
22. Round 11/01/2020 Leicester City - Southampton FC 1:2
23. Round 18/01/2020 Southampton FC - Wolverhampton Wanderers 2:3
24. Round 21/01/2020 Crystal Palace - Southampton FC 0:2
25. Round 01/02/2020 Liverpool FC - Southampton FC 4:0 yellow card
26. Round 15/02/2020 Southampton FC - Burnley FC 1:2
27. Round 22/02/2020 Southampton FC - Aston Villa 2:0
28. Round 29/02/2020 West Ham United - Southampton FC 3:1 yellow card
29. Round 07/03/2020 Southampton FC - Newcastle United 0:1
30. Round 19/06/2020 Norwich City - Southampton FC 0:3
31. Round 25/06/2020 Southampton FC - Arsenal FC 0:2 red card
33. Round 05/07/2020 Southampton FC - Manchester City 1:0
34. Round 09/07/2020 Everton FC - Southampton FC 1:1 yellow card
35. Round 13/07/2020 Manchester United - Southampton FC 2:2 yellow card
37. Round 19/07/2020 AFC Bournemouth - Southampton FC 0:2
38. Round 26/07/2020 Southampton FC - Sheffield United 3:1