| 1. Round | 29/08/2021 | Sevilla Atlético | - | CE Sabadell | 0:0 | ||||
| 2. Round | 05/09/2021 | CD Castellón | - | Sevilla Atlético | 2:0 | ||||
| 3. Round | 12/09/2021 | Atlético Sanluqueño CF | - | Sevilla Atlético | 1:0 | ||||
| 4. Round | 19/09/2021 | Sevilla Atlético | - | CD Alcoyano | 1:3 | ||||
| 12. Round | 14/11/2021 | Sevilla Atlético | - | FC Andorra | 1:1 | ||||
| 13. Round | 21/11/2021 | UE Cornellà | - | Sevilla Atlético | 1:2 | ||||
| 14. Round | 28/11/2021 | Sevilla Atlético | - | UE Costa Brava | 2:1 | ||||
| 15. Round | 05/12/2021 | Atlético Baleares | - | Sevilla Atlético | 0:2 | ||||
| 16. Round | 11/12/2021 | Sevilla Atlético | - | Real Madrid Castilla | 1:1 |  |
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| 17. Round | 19/12/2021 | Linares Deportivo | - | Sevilla Atlético | 4:0 | ||||
| 18. Round | 09/01/2022 | Sevilla Atlético | - | RB Linense | 1:0 |
Spain