1. Round 08/08/2021 FC Porto - Belenenses SAD 2:0
2. Round 15/08/2021 FC Famalicão - FC Porto 1:2
3. Round 22/08/2021 CS Marítimo - FC Porto 1:1 yellow card
4. Round 28/08/2021 FC Porto - FC Arouca 3:0 Goal
5. Round 11/09/2021 Sporting CP - FC Porto 1:1
6. Round 19/09/2021 FC Porto - Moreirense FC 5:0 GoalGoal
7. Round 24/09/2021 Gil Vicente - FC Porto 1:2 Goal
8. Round 02/10/2021 FC Porto - Paços de Ferreira 2:1 yellow-red card
9. Round 23/10/2021 CD Tondela - FC Porto 1:3 GoalGoalGoal
10. Round 30/10/2021 FC Porto - Boavista 4:1 yellow card
11. Round 07/11/2021 CD Santa Clara - FC Porto 0:3
12. Round 28/11/2021 FC Porto - Vitória Guimarães 2:1
13. Round 03/12/2021 Portimonense SC - FC Porto 0:3
14. Round 12/12/2021 FC Porto - Sporting Braga 1:0
15. Round 19/12/2021 FC Vizela - FC Porto 0:4
16. Round 30/12/2021 FC Porto - SL Benfica 3:1 Goal
17. Round 08/01/2022 GD Estoril - FC Porto 2:3 Goal
18. Round 16/01/2022 Belenenses SAD - FC Porto 1:4 Goal
19. Round 23/01/2022 FC Porto - FC Famalicão 3:1 Goal
21. Round 06/02/2022 FC Arouca - FC Porto 0:2
22. Round 11/02/2022 FC Porto - Sporting CP 2:2 Goal
23. Round 20/02/2022 Moreirense FC - FC Porto 0:1
24. Round 27/02/2022 FC Porto - Gil Vicente 1:1
25. Round 06/03/2022 Paços de Ferreira - FC Porto 2:4 Goal
26. Round 13/03/2022 FC Porto - CD Tondela 4:0 Goal
28. Round 04/04/2022 FC Porto - CD Santa Clara 3:0
29. Round 10/04/2022 Vitória Guimarães - FC Porto 0:1 Goal
30. Round 16/04/2022 FC Porto - Portimonense SC 7:0 GoalGoalGoal
31. Round 25/04/2022 Sporting Braga - FC Porto 1:0
32. Round 30/04/2022 FC Porto - FC Vizela 4:2 GoalGoal
33. Round 07/05/2022 SL Benfica - FC Porto 0:1 yellow card
34. Round 14/05/2022 FC Porto - GD Estoril 2:0