| 2. Round | 01/08/2021 | KS Cracovia | - | Śląsk Wrocław | 1:2 | ||||
| 3. Round | 08/08/2021 | Śląsk Wrocław | - | Lechia Gdańsk | 1:1 | ||||
| 4. Round | 15/08/2021 | Śląsk Wrocław | - | Górnik Łęczna | 0:0 | ||||
| 5. Round | 22/08/2021 | Piast Gliwice | - | Śląsk Wrocław | 1:1 | ||||
| 6. Round | 29/08/2021 | Zagłębie Lubin | - | Śląsk Wrocław | 1:3 | ||||
| 7. Round | 11/09/2021 | Śląsk Wrocław | - | Legia Warszawa | 1:0 |  |
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| 8. Round | 18/09/2021 | Radomiak Radom | - | Śląsk Wrocław | 1:1 | ||||
| 9. Round | 26/09/2021 | Śląsk Wrocław | - | Wisła Płock | 3:1 | ||||
| 10. Round | 02/10/2021 | Lech Poznań | - | Śląsk Wrocław | 4:0 | ||||
| 12. Round | 23/10/2021 | Wisła Kraków | - | Śląsk Wrocław | 0:5 | ||||
| 14. Round | 05/11/2021 | Śląsk Wrocław | - | Jagiellonia Białystok | 2:2 | ||||
| 15. Round | 21/11/2021 | Pogoń Szczecin | - | Śląsk Wrocław | 2:1 |  |
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| 18. Round | 13/12/2021 | Warta Poznań | - | Śląsk Wrocław | 2:1 |
Poland