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| 1st(1st leg) | KS Besëlidhja Lezhë | - | KF Skënderbeu | 1:2 (1:1) | ||
| 2nd (2nd leg) | KF Skënderbeu | - | KS Besëlidhja Lezhë | 3:0 (0:0) | ||
| 1st(1st leg): 22/01/2019 13:00 | 2nd (2nd leg): 06/02/2019 12:30 | Winner: KF Skënderbeu | ||||
| 1st(1st leg) | KS Kastrioti | - | FK Partizani | 2:4 (1:2) | ||
| 2nd (2nd leg) | FK Partizani | - | KS Kastrioti | 3:0 (1:0) | ||
| 1st(1st leg): 22/01/2019 13:00 | 2nd (2nd leg): 06/02/2019 12:30 | Winner: FK Partizani | ||||
| 1st(1st leg) | Egnatia Rrogozhine | - | Luftëtari Gjirokastër | 0:3 (0:0) | ||
| 2nd (2nd leg) | Luftëtari Gjirokastër | - | Egnatia Rrogozhine | 0:0 (0:0) | ||
| 1st(1st leg): 23/01/2019 13:00 | 2nd (2nd leg): 06/02/2019 12:30 | Winner: Luftëtari Gjirokastër | ||||
| 1st(1st leg) | FK Vllaznia | - | KS Kamza | 2:1 (0:1) | ||
| 2nd (2nd leg) | KS Kamza | - | FK Vllaznia | 1:0 (0:0) | ||
| 1st(1st leg): 23/01/2019 13:00 | 2nd (2nd leg): 06/02/2019 12:30 | Winner: KS Kamza | ||||
| 1st(1st leg) | KF Apolonia Fier | - | FK Kukësi | 2:1 (1:0) | ||
| 2nd (2nd leg) | FK Kukësi | - | KF Apolonia Fier | 2:0 (1:0) | ||
| 1st(1st leg): 23/01/2019 13:00 | 2nd (2nd leg): 06/02/2019 12:30 | Winner: FK Kukësi | ||||
| 1st(1st leg) | KF Bylis Ballsh | - | KF Laçi | 2:0 (0:0) | ||
| 2nd (2nd leg) | KF Laçi | - | KF Bylis Ballsh | 3:0 (3:0) | ||
| 1st(1st leg): 23/01/2019 13:00 | 2nd (2nd leg): 06/02/2019 12:30 | Winner: KF Laçi | ||||
| 1st(1st leg) | KF Lushnja | - | KF Teuta Durrës | 1:3 (0:2) | ||
| 2nd (2nd leg) | KF Teuta Durrës | - | KF Lushnja | 4:0 (2:0) | ||
| 1st(1st leg): 23/01/2019 13:00 | 2nd (2nd leg): 06/02/2019 12:30 | Winner: KF Teuta Durrës | ||||
| 1st(1st leg) | KF Tiranë | - | Flamurtari Vlorë | 2:0 (2:0) | ||
| 2nd (2nd leg) | Flamurtari Vlorë | - | KF Tiranë | 1:0 (0:0) | ||
| 1st(1st leg): 24/01/2019 12:00 | 2nd (2nd leg): 06/02/2019 12:30 | Winner: KF Tiranë | ||||
