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| 1st(1st leg) | KF Teuta Durrës | - | KF Laçi | 1:2 | ||
| 2nd (2nd leg) | KF Laçi | - | KF Teuta Durrës | 1:1 | ||
| 1st(1st leg): 30/03/2022 16:45 | 2nd (2nd leg): 13/04/2022 13:45 | Winner: KF Laçi | ||||
| 1st(1st leg) | FK Partizani | - | FK Vllaznia | 0:0 | ||
| 2nd (2nd leg) | FK Vllaznia | - | FK Partizani | 5:4 pso | ||
| 1st(1st leg): 31/03/2022 16:45 | 2nd (2nd leg): 13/04/2022 16:45 | Winner: FK Vllaznia | ||||
