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| 1st(1st leg) | Tigre | - | Racing Club | 2:0 (0:0) | ||
| 2nd (2nd leg) | Racing Club | - | Tigre | 2:1 (2:0) | ||
| 1st(1st leg): 11/05/2019 21:45 | 2nd (2nd leg): 14/05/2019 23:00 | Winner: Tigre | ||||
| 1st(1st leg) | Atlético Tucumán | - | River Plate | 3:0 (2:0) | ||
| 2nd (2nd leg) | River Plate | - | Atlético Tucumán | 4:1 (2:0) | ||
| 1st(1st leg): 12/05/2019 00:00 | 2nd (2nd leg): 15/05/2019 01:10 | Winner: Atlético Tucumán | ||||
| 1st(1st leg) | Argentinos Juniors | - | Gimnasia de La Plata | 0:0 (0:0) | ||
| 2nd (2nd leg) | Gimnasia de La Plata | - | Argentinos Juniors | 1:2 (0:1) | ||
| 1st(1st leg): 12/05/2019 21:45 | 2nd (2nd leg): 16/05/2019 23:00 | Winner: Argentinos Juniors | ||||
| 1st(1st leg) | Vélez Sarsfield | - | Boca Juniors | 0:0 (0:0) | ||
| 2nd (2nd leg) | Boca Juniors | - | Vélez Sarsfield | 5:4 (0:0, 0:0) pso | ||
| 1st(1st leg): 13/05/2019 00:00 | 2nd (2nd leg): 17/05/2019 01:10 | Winner: Boca Juniors | ||||
