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| 15/07/2022 | 01:00 | Central Córdoba SdE | - | Patronato de Paraná | 1:3 (0:1) | |
| 23:00 | Sarmiento de Junín | - | Defensa y Justicia | 2:0 (1:0) | ||
| 16/07/2022 | 01:30 | Arsenal de Sarandí | - | Platense | 1:1 (0:0) | |
| 01:30 | Aldosivi | - | Atlético Tucumán | 0:1 (0:1) | ||
| 17:00 | Barracas Central | - | Argentinos Juniors | 1:3 (1:1) | ||
| 19:30 | Gimnasia de La Plata | - | Colón de Santa Fe | 0:0 (0:0) | ||
| 19:30 | Independiente | - | Rosario Central | 0:0 (0:0) | ||
| 22:00 | Newell's Old Boys | - | Racing Club | 0:0 (0:0) | ||
| 17/07/2022 | 00:30 | Boca Juniors | - | Talleres de Córdoba | 1:0 (0:0) | |
| 17:00 | Godoy Cruz | - | Lanús | 2:1 (1:1) | ||
| 17:00 | Unión de Santa Fe | - | Huracán | 0:0 (0:0) | ||
| 19:30 | Banfield | - | San Lorenzo | 1:1 (1:1) | ||
| 22:00 | Tigre | - | Estudiantes | 2:1 (1:0) | ||
| 18/07/2022 | 00:30 | Vélez Sarsfield | - | River Plate | 2:2 (1:2) |
| » Tables | Home | Away | First round | Second round |
| # | Team | M. | W | D | L | goals | Dif. | Pt. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Godoy Cruz | 8 | 5 | 1 | 2 | 11:6 | 5 | 16 |
| 2 |
|
Newell's Old Boys | 8 | 4 | 4 | 0 | 9:4 | 5 | 16 |
| 3 |
|
Atlético Tucumán | 8 | 4 | 4 | 0 | 8:3 | 5 | 16 |
| 4 |
|
Argentinos Juniors | 8 | 5 | 1 | 2 | 12:8 | 4 | 16 |
| 5 |
|
Gimnasia de La Plata | 8 | 4 | 3 | 1 | 9:5 | 4 | 15 |
| 6 |
|
Huracán | 8 | 4 | 3 | 1 | 10:7 | 3 | 15 |
| 7 |
|
Racing Club | 8 | 4 | 2 | 2 | 12:6 | 6 | 14 |
| 8 |
|
Platense | 8 | 3 | 5 | 0 | 9:5 | 4 | 14 |
| 9 |
|
Unión de Santa Fe | 8 | 4 | 2 | 2 | 14:13 | 1 | 14 |
| 10 |
|
Banfield | 8 | 3 | 3 | 2 | 11:8 | 3 | 12 |
| 11 |
|
Boca Juniors | 8 | 4 | 0 | 4 | 13:13 | 0 | 12 |
| 12 |
|
San Lorenzo | 8 | 2 | 5 | 1 | 11:9 | 2 | 11 |
| 13 |
|
Arsenal de Sarandí | 8 | 2 | 5 | 1 | 10:9 | 1 | 11 |
| 14 |
|
Sarmiento de Junín | 8 | 3 | 2 | 3 | 8:7 | 1 | 11 |
| 15 |
|
Patronato de Paraná | 8 | 3 | 2 | 3 | 11:11 | 0 | 11 |
| 16 |
|
River Plate | 8 | 2 | 3 | 3 | 11:10 | 1 | 9 |
| 17 |
|
Colón de Santa Fe | 8 | 2 | 3 | 3 | 6:7 | -1 | 9 |
| 18 |
|
Tigre | 8 | 2 | 3 | 3 | 11:13 | -2 | 9 |
| 19 |
|
Barracas Central | 8 | 2 | 3 | 3 | 10:12 | -2 | 9 |
| 20 |
|
Central Córdoba SdE | 8 | 2 | 2 | 4 | 9:12 | -3 | 8 |
|
Estudiantes | 8 | 2 | 2 | 4 | 9:12 | -3 | 8 | |
| 22 |
|
Independiente | 8 | 2 | 2 | 4 | 7:11 | -4 | 8 |
| 23 |
|
Rosario Central | 8 | 2 | 2 | 4 | 3:7 | -4 | 8 |
| 24 |
|
Defensa y Justicia | 8 | 1 | 4 | 3 | 7:10 | -3 | 7 |
| 25 |
|
Vélez Sarsfield | 8 | 1 | 3 | 4 | 7:10 | -3 | 6 |
| 26 |
|
Talleres de Córdoba | 8 | 1 | 2 | 5 | 4:9 | -5 | 5 |
| 27 |
|
Lanús | 8 | 1 | 2 | 5 | 7:13 | -6 | 5 |
| 28 |
|
Aldosivi | 8 | 1 | 1 | 6 | 5:14 | -9 | 4 |
