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| 01/10/2021 | 19:00 | KVC Westerlo | - | Lommel SK | 2:0 (0:0) | |
| 02/10/2021 | 19:45 | Lierse Kempenzonen | - | Royal Excel Mouscron | 2:2 (1:1) | |
| 03/10/2021 | 15:00 | Waasland-Beveren | - | Excelsior Virton | 4:3 (1:3) | |
| 19:00 | SK Deinze | - | RWDM Brussels FC | 1:2 (1:0) |
| » Tables | Home | Away | First round | Second round |
| # | Team | M. | W | D | L | goals | Dif. | Pt. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
KVC Westerlo | 7 | 5 | 2 | 0 | 13:5 | 8 | 17 |
| 2 |
|
Waasland-Beveren | 7 | 4 | 0 | 3 | 15:12 | 3 | 12 |
| 3 |
|
Lierse Kempenzonen | 7 | 3 | 2 | 2 | 14:11 | 3 | 11 |
| 4 |
|
SK Deinze | 7 | 2 | 4 | 1 | 12:9 | 3 | 10 |
| 5 |
|
Lommel SK | 7 | 3 | 1 | 3 | 11:11 | 0 | 10 |
| 6 |
|
RWDM Brussels FC | 7 | 2 | 2 | 3 | 8:11 | -3 | 8 |
| 7 |
|
Excelsior Virton | 7 | 1 | 3 | 3 | 7:11 | -4 | 6 |
| 8 |
|
Royal Excel Mouscron | 7 | 0 | 2 | 5 | 6:16 | -10 | 2 |
| Promotion | |
| Playoffs | |
| Relegation |
