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| 17/09/2021 | 17:00 | FK Sarajevo | - | Leotar Trebinje | 0:1 (0:0) | |
| 19:00 | Borac Banja Luka | - | Široki Brijeg | 2:1 (2:1) | ||
| 18/09/2021 | 15:30 | HŠK Posušje | - | Radnik Bijeljina | 1:1 (0:1) | |
| 16:00 | Željezničar Sarajevo | - | Velež Mostar | 0:0 (0:0) | ||
| 17:55 | FK Tuzla City | - | Sloboda Tuzla | 1:0 (0:0) | ||
| 20:10 | Zrinjski Mostar | - | FK Rudar | 3:0 (2:0) |
| » Tables | Home | Away | First round | Second round |
| # | Team | M. | W | D | L | goals | Dif. | Pt. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
FK Tuzla City | 9 | 7 | 2 | 0 | 19:8 | 11 | 23 |
| 2 |
|
Zrinjski Mostar | 9 | 6 | 3 | 0 | 17:3 | 14 | 21 |
| 3 |
|
Sloboda Tuzla | 9 | 4 | 3 | 2 | 9:6 | 3 | 15 |
| 4 |
|
FK Sarajevo | 9 | 4 | 2 | 3 | 10:8 | 2 | 14 |
| 5 |
|
Željezničar Sarajevo | 9 | 2 | 5 | 2 | 6:7 | -1 | 11 |
| 6 |
|
Borac Banja Luka | 9 | 2 | 5 | 2 | 11:14 | -3 | 11 |
| 7 |
|
Široki Brijeg | 9 | 1 | 6 | 2 | 4:4 | 0 | 9 |
| 8 |
|
Velež Mostar | 9 | 3 | 3 | 3 | 8:9 | -1 | 9 |
| 9 |
|
FK Rudar | 9 | 2 | 2 | 5 | 9:13 | -4 | 8 |
| 10 |
|
Leotar Trebinje | 9 | 2 | 2 | 5 | 5:10 | -5 | 8 |
| 11 |
|
HŠK Posušje | 9 | 1 | 3 | 5 | 5:15 | -10 | 6 |
| 12 |
|
Radnik Bijeljina | 9 | 0 | 4 | 5 | 8:14 | -6 | 4 |
| Champions League Quali. | |
| Relegation |
