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| 07/08/2021 | 13:00 | Energetik-BGU Minsk | - | Neman Grodno | 0:4 (0:2) | |
| 15:00 | Sputnik Rechytsa | - | Dnyapro Mogilev | 0:3 dec. | ||
| 15:00 | FK Slutsk | - | Dinamo Minsk | 0:4 (0:2) | ||
| 17:00 | FK Vitebsk | - | Arsenal Dzerzhinsk | 5:4 (0:0, 0:0, 0:0) pso | ||
| 08/08/2021 | 13:30 | FK Slaviya Mozyr | - | BATE Borisov | 1:2 (0:1) | |
| 16:00 | Torpedo-BelAZ Zhodino | - | Lokomotiv Gomel | 5:4 (0:0, 0:0, 0:0) pso | ||
| 18:00 | Dinamo Brest | - | Rukh Brest | 2:0 (1:0) | ||
| 09/08/2021 | 17:00 | Shakhter Soligorsk | - | FK Gomel | 1:2 (1:0, 1:1) aet |
