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| 1st(1st leg) | Botafogo - PB | - | Londrina - PR | 0:2 (0:0) | ||
| 2nd (2nd leg) | Londrina - PR | - | Botafogo - PB | 3:3 (1:1) | ||
| 1st(1st leg): 13/03/2019 22:15 | 2nd (2nd leg): 04/04/2019 00:30 | Winner: Londrina - PR | ||||
| 1st(1st leg) | Ceará - CE | - | Corinthians SP | 1:3 (1:1) | ||
| 2nd (2nd leg) | Corinthians SP | - | Ceará - CE | 0:1 (0:0) | ||
| 1st(1st leg): 14/03/2019 00:30 | 2nd (2nd leg): 04/04/2019 01:30 | Winner: Corinthians SP | ||||
| 1st(1st leg) | Vasco da Gama - RJ | - | Avaí - SC | 3:2 (1:1) | ||
| 2nd (2nd leg) | Avaí - SC | - | Vasco da Gama - RJ | 0:1 (0:0) | ||
| 1st(1st leg): 15/03/2019 00:30 | 2nd (2nd leg): 11/04/2019 01:30 | Winner: Vasco da Gama - RJ | ||||
| 1st(1st leg) | Chapecoense | - | Criciúma - SC | 3:2 (2:0) | ||
| 2nd (2nd leg) | Criciúma - SC | - | Chapecoense | 0:2 (0:1) | ||
| 1st(1st leg): 27/03/2019 22:15 | 2nd (2nd leg): 10/04/2019 23:15 | Winner: Chapecoense | ||||
| 1st(1st leg) | CR Brasil - AL | - | Bahia - BA | 1:1 (1:0) | ||
| 2nd (2nd leg) | Bahia - BA | - | CR Brasil - AL | 1:0 (0:0) | ||
| 1st(1st leg): 02/04/2019 23:15 | 2nd (2nd leg): 09/04/2019 23:15 | Winner: Bahia - BA | ||||
| 1st(1st leg) | Luverdense - MT | - | Fluminense RJ | 0:0 (0:0) | ||
| 2nd (2nd leg) | Fluminense RJ | - | Luverdense - MT | 2:0 (0:0) | ||
| 1st(1st leg): 03/04/2019 23:15 | 2nd (2nd leg): 10/04/2019 23:15 | Winner: Fluminense RJ | ||||
| 1st(1st leg) | ABC - RN | - | Santa Cruz - PE | 1:0 (0:0) | ||
| 2nd (2nd leg) | Santa Cruz - PE | - | ABC - RN | 3:0 (2:0) | ||
| 1st(1st leg): 04/04/2019 01:30 | 2nd (2nd leg): 11/04/2019 01:30 | Winner: Santa Cruz - PE | ||||
| 1st(1st leg) | Atlético Goianiense | - | Santos FC | 1:0 (0:0) | ||
| 2nd (2nd leg) | Santos FC | - | Atlético Goianiense | 3:0 (1:0) | ||
| 1st(1st leg): 04/04/2019 23:15 | 2nd (2nd leg): 12/04/2019 01:30 | Winner: Santos FC | ||||
| 1st(1st leg) | Botafogo - RJ | - | Juventude - RS | 1:1 (0:1) | ||
| 2nd (2nd leg) | Juventude - RS | - | Botafogo - RJ | 2:1 (0:1) | ||
| 1st(1st leg): 05/04/2019 01:30 | 2nd (2nd leg): 11/04/2019 23:15 | Winner: Juventude - RS | ||||
| 1st(1st leg) | Vila Nova - GO | - | Bragantino - PA | 2:0 (1:0) | ||
| 2nd (2nd leg) | Bragantino - PA | - | Vila Nova - GO | 2:1 (1:1) | ||
| 1st(1st leg): 17/04/2019 00:00 | 2nd (2nd leg): 20/04/2019 20:00 | Winner: Vila Nova - GO | ||||
