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| 1st(1st leg) | Atlético Goianiense | - | Corinthians SP | 2:0 (1:0) | ||
| 2nd (2nd leg) | Corinthians SP | - | Atlético Goianiense | 4:1 (1:0) | ||
| 1st(1st leg): 28/07/2022 01:30 | 2nd (2nd leg): 18/08/2022 01:30 | Winner: Corinthians SP | ||||
| 1st(1st leg) | Flamengo RJ | - | Athletico Paranaense | 0:0 (0:0) | ||
| 2nd (2nd leg) | Athletico Paranaense | - | Flamengo RJ | 0:1 (0:0) | ||
| 1st(1st leg): 28/07/2022 01:30 | 2nd (2nd leg): 18/08/2022 01:30 | Winner: Flamengo RJ | ||||
| 1st(1st leg) | São Paulo FC | - | América - MG | 1:0 (1:0) | ||
| 2nd (2nd leg) | América - MG | - | São Paulo FC | 2:2 (1:2) | ||
| 1st(1st leg): 29/07/2022 00:00 | 2nd (2nd leg): 19/08/2022 01:00 | Winner: São Paulo FC | ||||
| 1st(1st leg) | Fortaleza | - | Fluminense RJ | 0:1 (0:1) | ||
| 2nd (2nd leg) | Fluminense RJ | - | Fortaleza | 2:2 (0:2) | ||
| 1st(1st leg): 29/07/2022 00:30 | 2nd (2nd leg): 18/08/2022 00:00 | Winner: Fluminense RJ | ||||
