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| 1st(1st leg) | Atlético de Alagoinhas - BA | - | Botafogo - PB | 1:1 (0:0) | ||
| 2nd (2nd leg) | Botafogo - PB | - | Atlético de Alagoinhas - BA | 3:0 (2:0) | ||
| 1st(1st leg): 16/12/2020 22:30 | 2nd (2nd leg): 23/12/2020 00:30 | Winner: Botafogo - PB | ||||
| 1st(1st leg) | Altos - PI | - | Globo - RN | 2:0 (1:0) | ||
| 2nd (2nd leg) | Globo - RN | - | Altos - PI | 1:0 (1:0) | ||
| 1st(1st leg): 23/12/2020 18:45 | 2nd (2nd leg): 30/12/2020 18:00 | Winner: Altos - PI | ||||
| 1st(1st leg) | Moto Club - MA | - | CSA - AL | 0:0 (0:0) | ||
| 2nd (2nd leg) | CSA - AL | - | Moto Club - MA | 2:0 (1:0) | ||
| 1st(1st leg): 06/01/2021 00:30 | 2nd (2nd leg): 27/01/2021 00:30 | Winner: CSA - AL | ||||
| 1st(1st leg) | Itabaiana - SE | - | Santa Cruz - PE | 2:2 (0:1) | ||
| 2nd (2nd leg) | Santa Cruz - PE | - | Itabaiana - SE | 2:0 (2:0) | ||
| 1st(1st leg): 27/01/2021 00:30 | 2nd (2nd leg): 03/02/2021 00:30 | Winner: Santa Cruz - PE | ||||
