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| 1st(1st leg) | Floresta - CE | - | Grêmio Novorizontino - SP | 1:1 (1:1) | ||
| 2nd (2nd leg) | Grêmio Novorizontino - SP | - | Floresta - CE | 0:2 (0:0) | ||
| 1st(1st leg): 16/01/2021 21:00 | 2nd (2nd leg): 23/01/2021 21:00 | Winner: Floresta - CE | ||||
| 1st(1st leg) | Mirassol - SP | - | Altos - PI | 4:0 (4:0) | ||
| 2nd (2nd leg) | Altos - PI | - | Mirassol - SP | 0:1 (0:1) | ||
| 1st(1st leg): 17/01/2021 19:00 | 2nd (2nd leg): 24/01/2021 18:45 | Winner: Mirassol - SP | ||||
