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| 1st(1st leg) | Coritiba - PR | - | Palmeiras | 1:3 (1:0) | ||
| 2nd (2nd leg) | Palmeiras | - | Coritiba - PR | 4:1 (1:0) | ||
| 1st(1st leg): 27/03/2019 19:00 | 2nd (2nd leg): 03/04/2019 19:00 | Winner: Palmeiras | ||||
| 1st(1st leg) | Tubarão - SC | - | Vasco da Gama | 1:2 (1:1) | ||
| 2nd (2nd leg) | Vasco da Gama | - | Tubarão - SC | 2:0 (0:0) | ||
| 1st(1st leg): 28/03/2019 00:00 | 2nd (2nd leg): 03/04/2019 19:00 | Winner: Vasco da Gama | ||||
| 1st(1st leg) | América - RN | - | Internacional | 0:3 (0:2) | ||
| 2nd (2nd leg) | Internacional | - | América - RN | 2:1 (1:1) | ||
| 1st(1st leg): 28/03/2019 19:00 | 2nd (2nd leg): 04/04/2019 19:00 | Winner: Internacional | ||||
| 1st(1st leg) | Chapecoense | - | Corinthians SP | 0:4 (0:3) | ||
| 2nd (2nd leg) | Corinthians SP | - | Chapecoense | 3:0 (2:0) | ||
| 1st(1st leg): 28/03/2019 21:00 | 2nd (2nd leg): 03/04/2019 19:00 | Winner: Corinthians SP | ||||
| 1st(1st leg) | Flamengo RJ | - | Real Ariquemes - RO | 4:2 (1:1) | ||
| 2nd (2nd leg) | Real Ariquemes - RO | - | Flamengo RJ | 0:10 (0:3) | ||
| 1st(1st leg): 28/03/2019 22:30 | 2nd (2nd leg): 05/04/2019 00:30 | Winner: Flamengo RJ | ||||
| 1st(1st leg) | CSA - AL | - | Grêmio Porto Alegre | 0:7 (0:3) | ||
| 2nd (2nd leg) | Grêmio Porto Alegre | - | CSA - AL | 0:0 (0:0) | ||
| 1st(1st leg): 28/03/2019 23:00 | 2nd (2nd leg): 04/04/2019 19:00 | Winner: Grêmio Porto Alegre | ||||
| 1st(1st leg) | Goiás - GO | - | Cruzeiro | 0:0 (0:0) | ||
| 2nd (2nd leg) | Cruzeiro | - | Goiás - GO | 3:2 (2:0) | ||
| 1st(1st leg): 29/03/2019 00:30 | 2nd (2nd leg): 03/04/2019 21:00 | Winner: Cruzeiro | ||||
| 1st(1st leg) | Fast Clube - AM | - | América - MG | 0:1 (0:0) | ||
| 2nd (2nd leg) | América - MG | - | Fast Clube - AM | 2:0 (0:0) | ||
| 1st(1st leg): 30/03/2019 01:00 | 2nd (2nd leg): 04/04/2019 19:00 | Winner: América - MG | ||||
