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| 1st(1st leg) | Olympique Lyon | - | Girondins Bordeaux | 3:1 (2:1) | ||
| 2nd (2nd leg) | Girondins Bordeaux | - | Olympique Lyon | 1:0 (1:0) | ||
| 1st(1st leg): 30/03/2010 19:45 | 2nd (2nd leg): 07/04/2010 19:45 | Winner: Olympique Lyon | ||||
| 1st(1st leg) | Bayern München | - | Manchester United | 2:1 (0:1) | ||
| 2nd (2nd leg) | Manchester United | - | Bayern München | 3:2 (3:1) | ||
| 1st(1st leg): 30/03/2010 19:45 | 2nd (2nd leg): 07/04/2010 19:45 | Winner: Bayern München | ||||
| 1st(1st leg) | Arsenal FC | - | FC Barcelona | 2:2 (0:0) | ||
| 2nd (2nd leg) | FC Barcelona | - | Arsenal FC | 4:1 (3:1) | ||
| 1st(1st leg): 31/03/2010 19:45 | 2nd (2nd leg): 06/04/2010 19:45 | Winner: FC Barcelona | ||||
| 1st(1st leg) | Inter | - | CSKA Moskva | 1:0 (0:0) | ||
| 2nd (2nd leg) | CSKA Moskva | - | Inter | 0:1 (0:1) | ||
| 1st(1st leg): 31/03/2010 19:45 | 2nd (2nd leg): 06/04/2010 17:30 | Winner: Inter | ||||
