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| 1st(1st leg) | Real Madrid | - | Tottenham Hotspur | 4:0 (1:0) | ||
| 2nd (2nd leg) | Tottenham Hotspur | - | Real Madrid | 0:1 (0:0) | ||
| 1st(1st leg): 05/04/2011 19:45 | 2nd (2nd leg): 13/04/2011 19:45 | Winner: Real Madrid | ||||
| 1st(1st leg) | Inter | - | FC Schalke 04 | 2:5 (2:2) | ||
| 2nd (2nd leg) | FC Schalke 04 | - | Inter | 2:1 (1:0) | ||
| 1st(1st leg): 05/04/2011 19:45 | 2nd (2nd leg): 13/04/2011 19:45 | Winner: FC Schalke 04 | ||||
| 1st(1st leg) | Chelsea FC | - | Manchester United | 0:1 (0:1) | ||
| 2nd (2nd leg) | Manchester United | - | Chelsea FC | 2:1 (1:0) | ||
| 1st(1st leg): 06/04/2011 19:45 | 2nd (2nd leg): 12/04/2011 19:45 | Winner: Manchester United | ||||
| 1st(1st leg) | FC Barcelona | - | Shakhtar Donetsk | 5:1 (2:0) | ||
| 2nd (2nd leg) | Shakhtar Donetsk | - | FC Barcelona | 0:1 (0:1) | ||
| 1st(1st leg): 06/04/2011 19:45 | 2nd (2nd leg): 12/04/2011 19:45 | Winner: FC Barcelona | ||||
