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| 1st(1st leg) | Puerto Montt | - | Unión San Felipe | 2:1 (1:1) | ||
| 2nd (2nd leg) | Unión San Felipe | - | Puerto Montt | 0:1 (0:0) | ||
| 1st(1st leg): 06/11/2022 16:00 | 2nd (2nd leg): 11/11/2022 21:00 | Winner: Puerto Montt | ||||
| 1st(1st leg) | Universidad de Concepción | - | Copiapó | 0:0 (0:0) | ||
| 2nd (2nd leg) | Copiapó | - | Universidad de Concepción | 5:1 (2:0) | ||
| 1st(1st leg): 07/11/2022 23:00 | 2nd (2nd leg): 11/11/2022 23:30 | Winner: Copiapó | ||||
