1st(1st leg) Deportivo Cali - Real San Andrés -:-
2nd (2nd leg) Real San Andrés - Deportivo Cali -:-
1st(1st leg): 31/07/2019 2nd (2nd leg): 14/08/2019
1st(1st leg) Deportes Tolima - Orsomarso SC -:-
2nd (2nd leg) Orsomarso SC - Deportes Tolima -:-
1st(1st leg): 31/07/2019 2nd (2nd leg): 14/08/2019
1st(1st leg) Atlético Nacional - Santa Fe -:-
2nd (2nd leg) Santa Fe - Atlético Nacional -:-
1st(1st leg): 31/07/2019 2nd (2nd leg): 14/08/2019
1st(1st leg) Atlético Junior - Atlético Bucaramanga -:-
2nd (2nd leg) Atlético Bucaramanga - Atlético Junior -:-
1st(1st leg): 31/07/2019 2nd (2nd leg): 14/08/2019
1st(1st leg) Once Caldas - América de Cali -:-
2nd (2nd leg) América de Cali - Once Caldas -:-
1st(1st leg): 31/07/2019 2nd (2nd leg): 14/08/2019
1st(1st leg) La Equidad - Deportivo Pasto -:-
2nd (2nd leg) Deportivo Pasto - La Equidad -:-
1st(1st leg): 31/07/2019 2nd (2nd leg): 14/08/2019
1st(1st leg) Rionegro Águilas Doradas - Deportivo Pereira -:-
2nd (2nd leg) Deportivo Pereira - Rionegro Águilas Doradas -:-
1st(1st leg): 31/07/2019 2nd (2nd leg): 14/08/2019
1st(1st leg) Independiente Medellín - Millonarios -:-
2nd (2nd leg) Millonarios - Independiente Medellín -:-
1st(1st leg): 31/07/2019 2nd (2nd leg): 14/08/2019