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| 1st(1st leg) | CF América | - | Sporting Cristal | 5:0 (2:0) | ||
| 2nd (2nd leg) | Sporting Cristal | - | CF América | 2:1 (0:0) | ||
| 1st(1st leg): 24/01/2007 | 2nd (2nd leg): 31/01/2007 | Winner: CF América | ||||
| 1st(1st leg) | Vélez Sarsfield | - | Danubio | 3:0 (1:0) | ||
| 2nd (2nd leg) | Danubio | - | Vélez Sarsfield | 1:2 (1:1) | ||
| 1st(1st leg): 30/01/2007 | 2nd (2nd leg): 06/02/2007 | Winner: Vélez Sarsfield | ||||
| 1st(1st leg) | Deportivo Táchira | - | Deportes Tolima | 1:2 (1:1) | ||
| 2nd (2nd leg) | Deportes Tolima | - | Deportivo Táchira | 2:0 (1:0) | ||
| 1st(1st leg): 30/01/2007 | 2nd (2nd leg): 08/02/2007 | Winner: Deportes Tolima | ||||
| 1st(1st leg) | Blooming | - | Santos FC | 0:1 (0:0) | ||
| 2nd (2nd leg) | Santos FC | - | Blooming | 5:0 (3:0) | ||
| 1st(1st leg): 31/01/2007 | 2nd (2nd leg): 07/02/2007 | Winner: Santos FC | ||||
| 1st(1st leg) | Cobreloa | - | Paraná Clube | 0:2 (0:1) | ||
| 2nd (2nd leg) | Paraná Clube | - | Cobreloa | 1:1 (0:0) | ||
| 1st(1st leg): 01/02/2007 | 2nd (2nd leg): 07/02/2007 | Winner: Paraná Clube | ||||
| 1st(1st leg) | Tacuary | - | LDU Quito | 1:1 (1:0) | ||
| 2nd (2nd leg) | LDU Quito | - | Tacuary | 3:0 (1:0) | ||
| 1st(1st leg): 01/02/2007 | 2nd (2nd leg): 06/02/2007 | Winner: LDU Quito | ||||
