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| 1st(1st leg) | CF América | - | LDU Quito | 1:1 (0:0) | ||
| 2nd (2nd leg) | LDU Quito | - | CF América | 0:0 (0:0) | ||
| 1st(1st leg): 28/05/2008 02:10 | 2nd (2nd leg): 04/06/2008 02:10 | Winner: LDU Quito | ||||
| 1st(1st leg) | Boca Juniors | - | Fluminense RJ | 2:2 (1:1) | ||
| 2nd (2nd leg) | Fluminense RJ | - | Boca Juniors | 3:1 (0:0) | ||
| 1st(1st leg): 29/05/2008 01:50 | 2nd (2nd leg): 05/06/2008 01:50 | Winner: Fluminense RJ | ||||
