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| 1st(1st leg) | Boca Juniors | - | Cerro Porteño | 1:1 (0:1) | ||
| 2nd (2nd leg) | Cerro Porteño | - | Boca Juniors | 7:8 (0:0, 0:0, 0:0) pso | ||
| 1st(1st leg): 27/10/2004 | 2nd (2nd leg): 10/11/2004 | Winner: Boca Juniors | ||||
| 1st(1st leg) | Arsenal de Sarandí | - | Bolívar | 1:0 (1:0) | ||
| 2nd (2nd leg) | Bolívar | - | Arsenal de Sarandí | 3:0 (1:0) | ||
| 1st(1st leg): 28/10/2004 | 2nd (2nd leg): 04/11/2004 | Winner: Bolívar | ||||
| 1st(1st leg) | Internacional | - | Atlético Junior | 1:0 (1:0) | ||
| 2nd (2nd leg) | Atlético Junior | - | Internacional | 1:1 (0:1) | ||
| 1st(1st leg): 03/11/2004 | 2nd (2nd leg): 10/11/2004 | Winner: Internacional | ||||
| 1st(1st leg) | LDU Quito | - | Santos FC | 3:2 (2:1) | ||
| 2nd (2nd leg) | Santos FC | - | LDU Quito | 1:2 (0:1) | ||
| 1st(1st leg): 03/11/2004 | 2nd (2nd leg): 10/11/2004 | Winner: LDU Quito | ||||
