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| 1st(1st leg) | Independiente | - | Independiente del Valle | 2:1 (0:0) | ||
| 2nd (2nd leg) | Independiente del Valle | - | Independiente | 1:0 (0:0) | ||
| 1st(1st leg): 07/08/2019 01:30 | 2nd (2nd leg): 14/08/2019 01:30 | Winner: Independiente del Valle | ||||
| 1st(1st leg) | Zulia FC | - | Colón de Santa Fe | 1:0 (0:0) | ||
| 2nd (2nd leg) | Colón de Santa Fe | - | Zulia FC | 4:0 (0:0) | ||
| 1st(1st leg): 08/08/2019 21:00 | 2nd (2nd leg): 16/08/2019 01:30 | Winner: Colón de Santa Fe | ||||
| 1st(1st leg) | Atlético Mineiro | - | La Equidad | 2:1 (1:1) | ||
| 2nd (2nd leg) | La Equidad | - | Atlético Mineiro | 1:3 (0:1) | ||
| 1st(1st leg): 21/08/2019 01:30 | 2nd (2nd leg): 28/08/2019 01:30 | Winner: Atlético Mineiro | ||||
| 1st(1st leg) | Corinthians SP | - | Fluminense RJ | 0:0 (0:0) | ||
| 2nd (2nd leg) | Fluminense RJ | - | Corinthians SP | 1:1 (0:0) | ||
| 1st(1st leg): 23/08/2019 01:30 | 2nd (2nd leg): 30/08/2019 01:30 | Winner: Corinthians SP | ||||
