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| 1st(1st leg) | AEK Larnaca | - | Ethnikos Achna | 1:2 (1:1) | ||
| 2nd (2nd leg) | Ethnikos Achna | - | AEK Larnaca | 3:1 (0:1) | ||
| 1st(1st leg): 26/04/2022 16:00 | 2nd (2nd leg): 04/05/2022 17:00 | Winner: Ethnikos Achna | ||||
| 1st(1st leg) | Anorthosis Famagusta | - | Omonia Nikosia | 0:2 (0:2) | ||
| 2nd (2nd leg) | Omonia Nikosia | - | Anorthosis Famagusta | 1:1 (1:1) | ||
| 1st(1st leg): 26/04/2022 17:00 | 2nd (2nd leg): 04/05/2022 17:00 | Winner: Omonia Nikosia | ||||
