01/12/2021 19:00 Birmingham City - Blackburn Rovers 1:5 (1:2)
19:00 Norwich City - Stoke City 2:3 (2:3)
02/12/2021 19:00 Exeter City - AFC Bournemouth 0:2 (0:1)
19:00 Derby County - Peterborough United 0:1 (0:1)
03/12/2021 19:00 Plymouth Argyle - Brighton & Hove Albion 1:2 (0:1)
04/12/2021 13:30 Northampton Town - Charlton Athletic 0:6 (0:2)
05/12/2021 13:30 Crewe Alexandra - Hull City 1:0 (0:0)
07/12/2021 19:00 Nottingham Forest - Bristol City 3:1 (1:1)
19:00 Aston Villa - Leicester City 0:2 (0:0)
19:00 Burnley FC - Luton Town 3:0 (2:0)
19:00 Coventry City - Leeds United 1:4 (0:0)
08/12/2021 19:00 Queens Park Rangers - Oldham Athletic 2:1 (0:0)
19:00 Wolverhampton Wanderers - Salford City 4:1 (3:0)
19:00 Cambridge United - Oxford United 4:2 (0:0, 2:2, 2:2) pso
19:00 Cardiff City - Watford FC 1:2 (0:0)
19:00 Sutton United - Preston North End 2:4 (1:1, 2:2, 2:2) pso
19:00 Barnsley FC - Crystal Palace 1:2 (0:0)
19:00 Rugby Town - Cheltenham Town 0:4 (0:2)
09/12/2021 19:00 Southampton FC - Sheffield Wednesday 0:1 (0:0)
19:00 Blackpool FC - Huddersfield Town 1:0 (1:0)
19:45 Bromley FC - Reading FC 1:3 (1:1, 1:1, 1:3) aet
10/12/2021 19:00 Everton FC - Fulham FC 3:2 (0:1)
19:00 Colchester United - Arsenal FC 3:0 (1:0)
19:00 West Ham United - Newcastle United 2:3 (0:0)
11/12/2021 12:30 Middlesbrough FC - Manchester City 0:3 (0:1)
17:30 Liverpool FC - Fleetwood Town 4:0 (3:0)
12/12/2021 12:00 Chelsea FC - Leyton Orient 4:1 (3:0)
13/12/2021 19:00 Manchester United - Scunthorpe United 4:2 (2:1)
14/12/2021 19:00 West Bromwich Albion - Rotherham United 3:2 (1:2)
19:00 Accrington Stanley - Swansea City 1:0 (0:0, 0:0, 1:0) aet
15/12/2021 19:00 Sheffield United - Millwall FC 1:1 (0:0, 1:1, 1:1) pso
16/12/2021 19:00 Tottenham Hotspur - Ipswich Town 5:1 (2:0)
U18 FA Youth Cup
U18 FA Youth Cup