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| 1st(1st leg) | Atlético Madrid | - | CP Mérida | 4:1 (0:1) | ||
| 2nd (2nd leg) | CP Mérida | - | Atlético Madrid | 4:4 (1:1) | ||
| 1st(1st leg): 28/11/1995 | 2nd (2nd leg): 13/12/1995 | Winner: Atlético Madrid | ||||
| 1st(1st leg) | UD Salamanca | - | Athletic Bilbao | 0:0 (0:0) | ||
| 2nd (2nd leg) | Athletic Bilbao | - | UD Salamanca | 3:1 (2:0) | ||
| 1st(1st leg): 29/11/1995 | 2nd (2nd leg): 14/12/1995 | Winner: Athletic Bilbao | ||||
| 1st(1st leg) | SD Compostela | - | Real Valladolid | 1:0 (1:0) | ||
| 2nd (2nd leg) | Real Valladolid | - | SD Compostela | 1:1 (0:0) | ||
| 1st(1st leg): 29/11/1995 | 2nd (2nd leg): 13/12/1995 | Winner: SD Compostela | ||||
| 1st(1st leg) | CD Leganés | - | Espanyol Barcelona | 0:1 (0:0) | ||
| 2nd (2nd leg) | Espanyol Barcelona | - | CD Leganés | 5:1 (3:1) | ||
| 1st(1st leg): 29/11/1995 | 2nd (2nd leg): 13/12/1995 | Winner: Espanyol Barcelona | ||||
| 1st(1st leg) | CD Numancia | - | Racing Santander | 0:0 (0:0) | ||
| 2nd (2nd leg) | Racing Santander | - | CD Numancia | 0:1 (0:1) | ||
| 1st(1st leg): 29/11/1995 | 2nd (2nd leg): 13/12/1995 | Winner: CD Numancia | ||||
| 1st(1st leg) | Écija Balompié | - | Sporting Gijón | 2:0 (1:0) | ||
| 2nd (2nd leg) | Sporting Gijón | - | Écija Balompié | 5:0 (1:0) | ||
| 1st(1st leg): 29/11/1995 | 2nd (2nd leg): 13/12/1995 | Winner: Sporting Gijón | ||||
| 1st(1st leg) | Levante UD | - | CD Tenerife | 1:0 (0:0) | ||
| 2nd (2nd leg) | CD Tenerife | - | Levante UD | 6:1 (3:0) | ||
| 1st(1st leg): 29/11/1995 | 2nd (2nd leg): 13/12/1995 | Winner: CD Tenerife | ||||
| 1st(1st leg) | FC Andorra | - | RC Celta | 0:5 (0:4) | ||
| 2nd (2nd leg) | RC Celta | - | FC Andorra | 2:0 (1:0) | ||
| 1st(1st leg): 29/11/1995 | 2nd (2nd leg): 13/12/1995 | Winner: RC Celta | ||||
| 1st(1st leg) | Hércules CF | - | Rayo Vallecano | 1:1 (0:1) | ||
| 2nd (2nd leg) | Rayo Vallecano | - | Hércules CF | 0:1 (0:1) | ||
| 1st(1st leg): 29/11/1995 | 2nd (2nd leg): 13/12/1995 | Winner: Hércules CF | ||||
| 1st(1st leg) | Real Oviedo | - | Valencia CF | 1:1 (0:0) | ||
| 2nd (2nd leg) | Valencia CF | - | Real Oviedo | 1:0 (1:0) | ||
| 1st(1st leg): 30/11/1995 | 2nd (2nd leg): 12/12/1995 | Winner: Valencia CF | ||||
