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| 1st(1st leg) | Getafe CF | - | Valencia CF | 1:0 (0:0) | ||
| 2nd (2nd leg) | Valencia CF | - | Getafe CF | 3:1 (0:1) | ||
| 1st(1st leg): 22/01/2019 20:30 | 2nd (2nd leg): 29/01/2019 20:30 | Winner: Valencia CF | ||||
| 1st(1st leg) | Sevilla FC | - | FC Barcelona | 2:0 (0:0) | ||
| 2nd (2nd leg) | FC Barcelona | - | Sevilla FC | 6:1 (2:0) | ||
| 1st(1st leg): 23/01/2019 20:30 | 2nd (2nd leg): 30/01/2019 20:30 | Winner: FC Barcelona | ||||
| 1st(1st leg) | Espanyol Barcelona | - | Real Betis | 1:1 (1:0) | ||
| 2nd (2nd leg) | Real Betis | - | Espanyol Barcelona | 3:1 (0:1, 1:1) aet | ||
| 1st(1st leg): 24/01/2019 18:30 | 2nd (2nd leg): 30/01/2019 18:30 | Winner: Real Betis | ||||
| 1st(1st leg) | Real Madrid | - | Girona FC | 4:2 (2:1) | ||
| 2nd (2nd leg) | Girona FC | - | Real Madrid | 1:3 (0:2) | ||
| 1st(1st leg): 24/01/2019 20:30 | 2nd (2nd leg): 31/01/2019 20:30 | Winner: Real Madrid | ||||
