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| 1st(1st leg) | CD Mirandés | - | Recreativo Huelva | 1:0 (1:0) | ||
| 2nd (2nd leg) | Recreativo Huelva | - | CD Mirandés | 1:1 (0:0) | ||
| 1st(1st leg): 09/06/2019 11:00 | 2nd (2nd leg): 16/06/2019 18:00 | Winner: CD Mirandés | ||||
| 1st(1st leg) | UD Melilla | - | Atlético Baleares | 0:0 (0:0) | ||
| 2nd (2nd leg) | Atlético Baleares | - | UD Melilla | 1:0 (1:0) | ||
| 1st(1st leg): 09/06/2019 17:30 | 2nd (2nd leg): 16/06/2019 17:00 | Winner: Atlético Baleares | ||||
| 1st(1st leg) | Hércules CF | - | UD Logroñés | 3:1 (0:0) | ||
| 2nd (2nd leg) | UD Logroñés | - | Hércules CF | 0:0 (0:0) | ||
| 1st(1st leg): 09/06/2019 17:45 | 2nd (2nd leg): 15/06/2019 17:30 | Winner: Hércules CF | ||||
| 1st(1st leg) | FC Cartagena | - | SD Ponferradina | 1:2 (1:0) | ||
| 2nd (2nd leg) | SD Ponferradina | - | FC Cartagena | 1:0 (0:0) | ||
| 1st(1st leg): 09/06/2019 18:30 | 2nd (2nd leg): 15/06/2019 19:30 | Winner: SD Ponferradina | ||||
