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| 1st(1st leg) | FC Barcelona | - | Glasgow City FC | 5:0 (3:0) | ||
| 2nd (2nd leg) | Glasgow City FC | - | FC Barcelona | 0:3 (0:1) | ||
| 1st(1st leg): 17/10/2018 17:30 | 2nd (2nd leg): 01/11/2018 19:30 | Winner: FC Barcelona | ||||
| 1st(1st leg) | Linköpings FC | - | Paris Saint-Germain | 0:2 (0:1) | ||
| 2nd (2nd leg) | Paris Saint-Germain | - | Linköpings FC | 3:2 (2:0) | ||
| 1st(1st leg): 17/10/2018 17:30 | 2nd (2nd leg): 31/10/2018 19:00 | Winner: Paris Saint-Germain | ||||
| 1st(1st leg) | Lillestrøm SK | - | Brøndby IF | 1:1 (1:1) | ||
| 2nd (2nd leg) | Brøndby IF | - | Lillestrøm SK | 0:2 (0:0) | ||
| 1st(1st leg): 17/10/2018 17:30 | 2nd (2nd leg): 31/10/2018 17:00 | Winner: Lillestrøm SK | ||||
| 1st(1st leg) | FC Zürich Frauen | - | Bayern München | 0:2 (0:2) | ||
| 2nd (2nd leg) | Bayern München | - | FC Zürich Frauen | 3:0 (1:0) | ||
| 1st(1st leg): 17/10/2018 18:00 | 2nd (2nd leg): 31/10/2018 18:00 | Winner: Bayern München | ||||
| 1st(1st leg) | VfL Wolfsburg | - | Atlético Madrid | 4:0 (0:0) | ||
| 2nd (2nd leg) | Atlético Madrid | - | VfL Wolfsburg | 0:6 (0:1) | ||
| 1st(1st leg): 17/10/2018 18:00 | 2nd (2nd leg): 31/10/2018 19:00 | Winner: VfL Wolfsburg | ||||
| 1st(1st leg) | AFC Ajax | - | Olympique Lyon | 0:4 (0:2) | ||
| 2nd (2nd leg) | Olympique Lyon | - | AFC Ajax | 9:0 (4:0) | ||
| 1st(1st leg): 17/10/2018 18:00 | 2nd (2nd leg): 31/10/2018 18:00 | Winner: Olympique Lyon | ||||
| 1st(1st leg) | Chelsea FC Women | - | ACF Fiorentina | 1:0 (1:0) | ||
| 2nd (2nd leg) | ACF Fiorentina | - | Chelsea FC Women | 0:6 (0:2) | ||
| 1st(1st leg): 17/10/2018 19:35 | 2nd (2nd leg): 31/10/2018 18:30 | Winner: Chelsea FC Women | ||||
| 1st(1st leg) | FC Rosengård | - | Slavia Praha | 2:3 (1:2) | ||
| 2nd (2nd leg) | Slavia Praha | - | FC Rosengård | 0:0 (0:0) | ||
| 1st(1st leg): 18/10/2018 18:00 | 2nd (2nd leg): 01/11/2018 17:30 | Winner: Slavia Praha | ||||
