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| 10/11/2010 | 09:30 | Lokomotiv Tbilisi | - | FC Olimpi Rustavi | 0:2 (0:0) | |
| 09:30 | Dinamo Batumi | - | FC Zestafoni | 1:2 (1:1) | ||
| 09:30 | Chikhura Sachkhere | - | Dinamo Tbilisi | 0:4 (0:2) | ||
| 09:30 | FC Merani Martvili | - | Sioni Bolnisi | 2:4 (0:0, 0:0, 0:0) pso | ||
| 09:30 | Spartak Tskhinvali | - | FC Samtredia | 1:0 (0:0) | ||
| 09:30 | FC Gagra | - | Kolkheti Poti | 1:0 (0:0) | ||
| 09:30 | Squri Tsalenjikha | - | WIT Georgia | 1:2 (0:0, 1:1) aet | ||
| 14:00 | Torpedo Kutaisi | - | Baia Zugdidi | 1:0 (0:0, 0:0) aet |
