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| 06/11/2022 | 00:00 | Comunicaciones | - | Cobán Imperial | 2:2 (2:0) | |
| 00:00 | Deportivo Mixco | - | Santa Lucía | 0:0 (0:0) | ||
| 02:00 | Antigua GFC | - | Iztapa | 4:1 (1:1) | ||
| 17:00 | Deportivo Guastatoya | - | CSD Municipal | 1:3 (1:2) | ||
| 19:15 | Deportivo Malacateco | - | Achuapa | 1:0 (0:0) | ||
| 23:00 | Deportivo Xinabajul | - | Xelaju MC | 0:2 (0:1) |
| » Tables | Home | Away | First round | Second round |
| # | Team | M. | W | D | L | goals | Dif. | Pt. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Antigua GFC | 18 | 10 | 4 | 4 | 38:23 | 15 | 34 |
| 2 |
|
Comunicaciones | 18 | 9 | 6 | 3 | 28:19 | 9 | 33 |
| 3 |
|
Cobán Imperial | 18 | 8 | 5 | 5 | 28:24 | 4 | 29 |
| 4 |
|
Deportivo Malacateco | 18 | 8 | 4 | 6 | 24:20 | 4 | 28 |
| 5 |
|
Xelaju MC | 18 | 6 | 6 | 6 | 23:18 | 5 | 24 |
| 6 |
|
CSD Municipal | 18 | 6 | 5 | 7 | 26:21 | 5 | 23 |
| 7 |
|
Deportivo Guastatoya | 18 | 5 | 8 | 5 | 15:15 | 0 | 23 |
| 8 |
|
Iztapa | 18 | 6 | 5 | 7 | 27:29 | -2 | 23 |
| 9 |
|
Deportivo Xinabajul | 18 | 6 | 5 | 7 | 20:22 | -2 | 23 |
| 10 |
|
Achuapa | 18 | 5 | 6 | 7 | 20:32 | -12 | 21 |
| 11 |
|
Santa Lucía | 18 | 3 | 6 | 9 | 17:29 | -12 | 15 |
| 12 |
|
Deportivo Mixco | 18 | 2 | 8 | 8 | 12:26 | -14 | 14 |
| Playoffs |
