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| 1st(1st leg) | Torino FC | - | Sampdoria | 0:2 (0:0) | ||
| 2nd (2nd leg) | Sampdoria | - | Torino FC | 1:2 (0:0) | ||
| 1st(1st leg): 19/11/2004 14:00 | 2nd (2nd leg): 12/01/2005 19:30 | Winner: Sampdoria | ||||
| 1st(1st leg) | AS Roma | - | AC Siena | 1:2 (0:1) | ||
| 2nd (2nd leg) | AC Siena | - | AS Roma | 1:5 (1:2) | ||
| 1st(1st leg): 19/11/2004 16:00 | 2nd (2nd leg): 13/01/2005 16:30 | Winner: AS Roma | ||||
| 1st(1st leg) | Atalanta | - | Juventus | 2:0 (0:0) | ||
| 2nd (2nd leg) | Juventus | - | Atalanta | 3:3 (2:2) | ||
| 1st(1st leg): 19/11/2004 20:00 | 2nd (2nd leg): 13/01/2005 20:00 | Winner: Atalanta | ||||
| 1st(1st leg) | US Lecce | - | Udinese Calcio | 4:5 (3:2) | ||
| 2nd (2nd leg) | Udinese Calcio | - | US Lecce | 3:4 (1:1) | ||
| 1st(1st leg): 20/11/2004 14:00 | 2nd (2nd leg): 13/01/2005 14:00 | Winner: Udinese Calcio | ||||
| 1st(1st leg) | ACF Fiorentina | - | Parma FC | 2:0 (1:0) | ||
| 2nd (2nd leg) | Parma FC | - | ACF Fiorentina | 0:3 (0:0) | ||
| 1st(1st leg): 20/11/2004 16:00 | 2nd (2nd leg): 12/01/2005 14:00 | Winner: ACF Fiorentina | ||||
| 1st(1st leg) | US Palermo | - | AC Milan | 1:2 (0:0) | ||
| 2nd (2nd leg) | AC Milan | - | US Palermo | 2:0 (1:0) | ||
| 1st(1st leg): 20/11/2004 20:00 | 2nd (2nd leg): 12/01/2005 20:00 | Winner: AC Milan | ||||
| 1st(1st leg) | Cagliari Calcio | - | Lazio Roma | 2:1 (1:0) | ||
| 2nd (2nd leg) | Lazio Roma | - | Cagliari Calcio | 3:2 (1:0, 2:1) aet | ||
| 1st(1st leg): 21/11/2004 15:00 | 2nd (2nd leg): 13/01/2005 14:00 | Winner: Cagliari Calcio | ||||
| 1st(1st leg) | Inter | - | Bologna FC | 3:1 (1:1) | ||
| 2nd (2nd leg) | Bologna FC | - | Inter | 1:3 (1:0) | ||
| 1st(1st leg): 21/11/2004 20:00 | 2nd (2nd leg): 12/01/2005 16:30 | Winner: Inter | ||||
