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| 1st(1st leg) | Deportivo Guadalajara | - | UANL Tigres | 1:2 (0:1) | ||
| 2nd (2nd leg) | UANL Tigres | - | Deportivo Guadalajara | 5:3 (3:1) | ||
| 1st(1st leg): 25/05/2021 03:00 | 2nd (2nd leg): 01/06/2021 01:00 | Winner: UANL Tigres | ||||
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| 1st(1st leg) | Deportivo Guadalajara | - | UANL Tigres | 1:2 (0:1) | ||
| 2nd (2nd leg) | UANL Tigres | - | Deportivo Guadalajara | 5:3 (3:1) | ||
| 1st(1st leg): 25/05/2021 03:00 | 2nd (2nd leg): 01/06/2021 01:00 | Winner: UANL Tigres | ||||
