 |
 |
|
|
| 04/02/2022 | 23:00 | Gallos Blancos | - | Deportivo Guadalajara | 2:2 (2:1) | |
| 05/02/2022 | 02:00 | Mazatlán FC | - | UANL Tigres | 2:4 (2:3) | |
| 18:00 | Cruz Azul | - | CF América | 1:3 (0:0) | ||
| 06/02/2022 | 18:00 | Puebla FC | - | Club Tijuana | 2:0 (1:0) | |
| 23:00 | Atlético San Luis | - | Deportivo Toluca | 2:2 (0:1) | ||
| 07/02/2022 | 23:00 | CF Pachuca | - | FC Juárez | 3:1 (3:0) | |
| 23:00 | Club Necaxa | - | Atlas Guadalajara | 1:1 (1:1) | ||
| 08/02/2022 | 01:00 | CF Monterrey | - | Pumas UNAM | 5:2 (5:0) | |
| 01:00 | Santos Laguna | - | Club León | 1:3 (1:2) |
| » Tables | Home | Away | First round | Second round |
| # | Team | M. | W | D | L | goals | Dif. | Pt. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
CF Monterrey | 6 | 6 | 0 | 0 | 20:3 | 17 | 18 |
| 2 |
|
CF Pachuca | 6 | 5 | 0 | 1 | 14:7 | 7 | 15 |
| 3 |
|
UANL Tigres | 6 | 4 | 2 | 0 | 16:7 | 9 | 14 |
| 4 |
|
Deportivo Guadalajara | 6 | 4 | 2 | 0 | 13:4 | 9 | 14 |
| 5 |
|
CF América | 6 | 4 | 1 | 1 | 12:5 | 7 | 13 |
| 6 |
|
Atlas Guadalajara | 6 | 2 | 3 | 1 | 6:8 | -2 | 9 |
| 7 |
|
Pumas UNAM | 6 | 2 | 1 | 3 | 7:7 | 0 | 7 |
| 8 |
|
Club Tijuana | 6 | 1 | 4 | 1 | 9:10 | -1 | 7 |
| 9 |
|
Club León | 6 | 2 | 1 | 3 | 9:11 | -2 | 7 |
| 10 |
|
Cruz Azul | 6 | 2 | 1 | 3 | 5:7 | -2 | 7 |
| 11 |
|
Atlético San Luis | 6 | 1 | 3 | 2 | 7:10 | -3 | 6 |
| 12 |
|
Deportivo Toluca | 6 | 1 | 2 | 3 | 9:12 | -3 | 5 |
| 13 |
|
Gallos Blancos | 6 | 1 | 2 | 3 | 5:11 | -6 | 5 |
|
Mazatlán FC | 6 | 1 | 2 | 3 | 5:11 | -6 | 5 | |
| 15 |
|
Club Necaxa | 6 | 1 | 2 | 3 | 4:11 | -7 | 5 |
| 16 |
|
Puebla FC | 6 | 1 | 1 | 4 | 4:9 | -5 | 4 |
| 17 |
|
Santos Laguna | 6 | 1 | 1 | 4 | 4:11 | -7 | 4 |
| 18 |
|
FC Juárez | 6 | 1 | 0 | 5 | 6:11 | -5 | 3 |
| Playoffs |
