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| 1st(1st leg) | CF América | - | UANL Tigres | 0:1 (0:0) | ||
| 2nd (2nd leg) | UANL Tigres | - | CF América | 2:0 (1:0) | ||
| 1st(1st leg): 12/11/2022 02:00 | 2nd (2nd leg): 15/11/2022 02:00 | Winner: UANL Tigres | ||||
|
|
|
| 1st(1st leg) | CF América | - | UANL Tigres | 0:1 (0:0) | ||
| 2nd (2nd leg) | UANL Tigres | - | CF América | 2:0 (1:0) | ||
| 1st(1st leg): 12/11/2022 02:00 | 2nd (2nd leg): 15/11/2022 02:00 | Winner: UANL Tigres | ||||
